Replengen Deep

(8 customer reviews)

32,00 

Buy Replengen Deep online through Botoderm to equip your aesthetic practice with a highly versatile, advanced-viscosity South Korean dermal filler. Manufactured by Reanzen Co., Ltd., Replengen Deep is formulated using premium Shiseido Hyaluronic Acid (24mg/mL) integrated with 0.3% Lidocaine for optimal patient comfort. Utilizing proprietary GI (Grinding Irregular) Technology, the gel particles are finely and uniformly divided, ensuring an exceptionally smooth extrusion force. Combined with HAMC (Hyaluronic Acid Moisture Correction) Technology for superior cross-linking, it provides reliable lifting capacity. It is the premier clinical choice for correcting moderate-to-deep facial wrinkles—such as severe nasolabial folds—and providing elegant, structural lip augmentation.

  • Composition: 24 mg/mL Cross-linked HA + 0.3% Lidocaine
  • Volume: 1 x 1.1mL pre-filled sterile syringe
  • Manufacturer: Reanzen Co., Ltd. (South Korea)
  • Clinical Indication: Mid-to-deep dermis injection for deep wrinkles, severe nasolabial folds, and lip contouring
Description

Advanced Wrinkle Correction and Lip Augmentation with Replengen Deep

Buy Replengen Deep online to provide your aesthetic patients with a highly precise, exceptionally versatile Hyaluronic Acid dermal filler. Developed by the renowned South Korean biopharmaceutical manufacturer Reanzen Co., Ltd., the Replengen line is celebrated globally by elite injectors for its supreme purity and exceptionally smooth injection profile. Formulated exclusively with premium pharmaceutical-grade Hyaluronic Acid sourced from Shiseido (Japan), Replengen Deep offers the perfect rheological “sweet spot.” It provides the structural G-prime required to lift and erase deep facial creases, yet remains soft and malleable enough to create beautifully plump, natural-feeling lips with sharp definition.

Uncompromised Smoothness & Purity: GI and HAMC Technologies

The predictability, longevity, and safety of a dermal filler are largely determined by its particle size and cross-linking science. Replengen Deep stands out by utilizing proprietary GI (Grinding Irregular) Technology. This advanced manufacturing process finely divides the gel particles into an incredibly uniform size, ensuring that the extrusion force required by the practitioner remains perfectly consistent from the first drop to the last. This translates to an incredibly smooth, painless injection with zero blockages. Furthermore, Reanzen utilizes HAMC (Hyaluronic Acid Moisture Correction) Technology to tightly control the cross-linking process. This dramatically delays the natural decomposition of the HA within the body, ensuring long-lasting, durable results while maintaining minimal residual BDDE for ultimate clinical safety.

Clinical Indications & Targeted Treatment Areas

Because of its perfectly balanced medium-to-firm viscosity, Replengen Deep is arguably the most heavily utilized filler in the Reanzen portfolio for structural soft-tissue enhancement. It provides dual-action support for both volume restoration and contouring:

  • Structural Lip Augmentation: The ideal choice for adding palpable volume to the mucosal tissue, executing crisp vermilion border definition, and performing advanced techniques like the “Russian Lip.”
  • Deep Nasolabial Folds: Filling and powerfully lifting deep, entrenched smile lines that run from the nose to the corners of the mouth, restoring a rested mid-face.
  • Marionette Lines: Elevating and smoothing the oral commissures to correct a “downturned” mouth and provide fundamental structural support to the lower face.
  • Deep Glabellar Lines: Treating severe, static frown lines between the eyebrows where neurotoxin alone is no longer sufficient to lift the crease.

Efficacy Timeline and Patient Comfort

To ensure a premium, pain-free patient experience—especially in highly sensitive, vascular areas like the lips—Replengen Deep is formulated with 0.3% Lidocaine Hydrochloride, providing immediate local anesthesia upon injection.

  • Immediate Results: The volumizing and smoothing effects of the highly uniform HA gel are visible immediately upon injection.
  • Tissue Integration: The GI-stabilized gel integrates seamlessly with the surrounding mid-to-deep dermal tissue within 1 to 2 weeks, providing a completely natural, undetectable feel during facial expressions.
  • Duration: Thanks to the HAMC cross-linking process delaying enzymatic degradation, aesthetic results typically endure for 12 to 18 months, naturally tapering based on patient metabolism and the structural mobility of the treatment area.

Technical Specifications

ParameterClinical Specification
Product NameReplengen Deep with Lidocaine
Active SubstrateCross-linked Hyaluronic Acid (HA) 24 mg/mL (Shiseido Raw Material)
Anesthetic AddedLidocaine Hydrochloride 0.3%
Packaging Volume1 x 1.1mL pre-filled syringe per box
Needle Size2 x 27G sterile needles included
Injection DepthMid to deep dermis
Storage NeedsStore between 2°C and 25°C. Keep away from direct sunlight. Do not freeze.

Frequently Asked Questions (FAQ)

What is the difference between Replengen Deep and Replengen Volume?

Replengen Deep is a medium-to-firm viscosity filler designed for the mid-to-deep dermis to treat deep wrinkles and provide structural lip augmentation. Replengen Volume is a thicker, much harder formulation (higher G-prime) designed exclusively for deep subcutaneous or supraperiosteal (on-the-bone) injection to heavily contour the cheeks, chin, and jawline.

Why does Replengen use Shiseido Hyaluronic Acid?

Shiseido (Japan) produces some of the highest-quality, most highly purified raw hyaluronic acid in the global pharmaceutical market. By sourcing their raw HA from Shiseido, Reanzen guarantees that the base material for Replengen Deep is exceptionally pure, vastly reducing the risk of allergic reactions and ensuring a premium final product.

How should Replengen Deep be stored?

Unlike botulinum toxins, hyaluronic acid dermal fillers do not require strict cold-chain refrigeration. Replengen Deep is highly stable at room temperature and should be stored securely between 2°C and 25°C. Never freeze the product, as freezing temperatures will permanently destroy the HAMC cross-linked HA matrix.


Professional Medical Procurement Disclaimer: Replengen Deep is a professional-grade Class III medical device restricted exclusively to licensed healthcare professionals, dermatologists, and certified aesthetic injectors. Botoderm assumes absolutely no clinical or legal liability for adverse reactions, vascular compromise, necrosis, complications, or loss of product efficacy due to unauthorized self-administration, improper injection depth, or poor handling post-delivery.

Reviews (8)

8 reviews for Replengen Deep

  1. Avatar Of Goals

    Goals (verified owner)

    Excellent filler for the perfect pout! Great company to trust in for safe products.

  2. Avatar Of Jackie2252

    Jackie2252 (verified owner)

    Love the results after just one syringe!

  3. Avatar Of Jackie2252

    Jackie2252 (verified owner)

    So smooth and easy to inject!

  4. Avatar Of Aric Kalisi

    Aric Kalisi (verified owner)

    I bought this many times and have never had an issue, it works great. I love Derma solution. Fast shipping, great prices.

  5. Avatar Of Niqui Messmer

    Niqui Messmer (verified owner)

    Excellent product! Every single purchase has been easy.. even when their usual payment method services are down. So responsive. Products authentic and highest quality

  6. Avatar Of Miguel Ángel Garcia Flores

    Miguel Ángel Garcia Flores (verified owner)

    I’ve been using this dermafiller and I’m genuinely impressed with the results. It delivers noticeable improvement in skin texture and volume, leaving my skin looking refreshed and more

  7. Avatar Of Sabrina Torres

    Sabrina Torres (verified owner)

    I liked the effect of this one specially in cheekbones and deep lines. It applies easily and comfortably, great density and purity. No downtime. I’ll recommend this brand.

  8. Avatar Of Jackie2252

    Jackie2252 (verified owner)

    Healed lips from one syringe. A+++

Only logged in customers who have purchased this product may leave a review.

About Replengen

Authentic Replengen Fillers by Reanzen

Buy Replengen online to supply your advanced aesthetic practice with a highly refined, technologically advanced Hyaluronic Acid dermal filler portfolio. Manufactured in South Korea by the esteemed biopharmaceutical company Reanzen Co., Ltd., the Replengen series is globally celebrated by elite injectors for its incredibly smooth injection profile and unparalleled raw material purity. Uniquely within the Korean filler market, Replengen is formulated exclusively with pharmaceutical-grade Hyaluronic Acid sourced from Shiseido (Japan), guaranteeing an ultra-pure, low-toxicity base. By integrating proprietary GI (Grinding Irregular) and HAMC (Hyaluronic Acid Moisture Correction) Technologies, this premier portfolio delivers exceptional longevity, massive lifting capacity, and perfectly uniform gel extrusion. Explore our authentic Replengen wholesale inventory—including Fine, Deep, and Volume—each integrated with 0.3% Lidocaine for maximum patient comfort.

The Clinical Superiority of Shiseido HA, GI, and HAMC Technologies

In the highly competitive medical aesthetics market, a dermal filler's predictability, longevity, and patient safety are determined by its base ingredients and cross-linking science. The Replengen portfolio stands apart through a trifecta of clinical advantages:

  • Shiseido Raw Hyaluronic Acid: By sourcing base HA from Shiseido (Japan)—one of the world's leading producers of highly purified, pharmaceutical-grade HA—Reanzen ensures the final gel matrix boasts near-zero impurities, drastically minimizing the risk of allergic reactions and post-injection inflammation.
  • GI (Grinding Irregular) Technology: This proprietary manufacturing process finely and evenly divides the cross-linked gel particles. For the treating physician, this ensures that the extrusion force remains flawlessly smooth and perfectly consistent from the first drop to the last, eliminating blockages even when using ultra-fine needles.
  • HAMC (Hyaluronic Acid Moisture Correction) Technology: This highly efficient cross-linking methodology tightly binds the HA molecules, dramatically delaying the body's natural enzymatic decomposition. This ensures highly durable, long-lasting aesthetic results while keeping residual BDDE at exceptionally low, safe levels.

The Comprehensive Replengen Portfolio

To support your clinic's highly specific treatment protocols, the Replengen line is meticulously divided into specialized rheological profiles, all featuring 24 mg/mL of premium HA and 0.3% Lidocaine:

  • Replengen Fine: The softest, lowest-viscosity formulation. Engineered for injection into the superficial dermis to seamlessly hydrate the skin and correct delicate fine lines, periorbital wrinkles (crow's feet), and superficial perioral rhytides without causing the Tyndall effect.
  • Replengen Deep: The highly versatile, medium-viscosity baseline formulation. Designed for the mid-to-deep dermis, it is the absolute clinical standard for treating moderate-to-deep wrinkles, correcting nasolabial folds, and providing elegant, structural lip augmentation.
  • Replengen Volume: The thickest, most structural, highest-lifting gel available. Boasting massive G-prime (elasticity), this formulation is reserved exclusively for deep subcutaneous and supraperiosteal (on-the-bone) injection to execute dramatic jawline sculpting, cheek volumization, chin projection, and severe volume reconstruction.

Frequently Asked Questions About Replengen Wholesale

Who manufactures Replengen dermal fillers?

The Replengen series is researched, developed, and manufactured by Reanzen Co., Ltd., a highly respected South Korean biopharmaceutical manufacturer. They are globally recognized for their stringent quality control standards and their strategic partnership utilizing premium Japanese HA raw materials.

Do Replengen HA fillers require cold-chain refrigeration?

No. Unlike highly sensitive biologic neuromodulators, hyaluronic acid dermal fillers like Replengen are exceptionally stable at room temperature. They should be stored securely between 2°C and 25°C. You must never freeze the product, as freezing temperatures will permanently destroy the stabilized HAMC cross-linked HA matrix.

Are wholesale purchases of Replengen restricted?

Yes. The Replengen series consists of professional-grade Class III medical devices. To ensure absolute patient safety, mitigate the risk of vascular compromise, and comply with strict international medical distribution laws, wholesale access on Botoderm is legally restricted exclusively to licensed healthcare professionals, certified dermatologists, plastic surgeons, and verified aesthetic injectors.


Professional Medical Procurement Disclaimer: The manufacturing details, technical specifications, and clinical guidelines featured on this brand page are intended purely for commercial B2B procurement and medical supply planning. Botoderm assumes absolutely no clinical or legal liability for adverse reactions, vascular occlusion, necrosis, complications, or loss of product efficacy due to unauthorized use, improper injection depth, or third-party negligence post-delivery.

Details

Details

Replengen Deep is a painless hyaluronic filler for restoring and improving of the aged skin.

Purpose: 

  • Face contouring
  • Create and enhance a radiant glow
  • Removal of scars and stretch marks
  • Lip contouring
  • Removal wrinkles around the eyes
  • Rhinoplasty

 

Benefits of REPLENGEN Products:

  1. Painless injection
  2. Excellent quality
  3. Extra moisturizing
  4. Fast and safe result
  5. Easy to use
  6. Super duration (HAMC technology)

Storage:

  • Store at 2-25 degrees Celsius
  • Expiry date is 24 months from manufacturing date
  • Don’t freeze or heat the product

 

ReplengenFineVolumeDeep
Package1 syringe – 1.1mL

2 needle x 30G 

1 syringe – 1.1mL

2 needle x 25G 

1 syringe – 1.1mL

2 needle x 27G 

PurposeFacial skin

Nose

Nasolabial wrinkles

Cheeks

Cheekbones

Chin 

deep wrinkles

nose

cheeks

chin

nasolabial folds

around the eyes (crow’s feet)

perioral lines

lip contouring

marionette lines

forehead

Effect duration6-8 months12+ months9-12 months

The product has contraindications. We are not responsible for any negative effects that you may encounter after administering products by yourself. It is recommended to consult a doctor or medical professional for any procedure.









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